異位性皮膚炎往往不只皮膚出問題，多會合併其它疾患，皮膚病況嚴重者更是如此，而且皮膚問題事實上與腸道密切相關。
異位性皮膚炎時常合併睡眠障礙、消化問題、氣喘、過敏性鼻炎、身心症，而正值青春期的患者又須考量長高發育等。
不只能治療皮膚，還同步處理多個身體不適，讓皮膚達到從裡到外的改變，正是中醫所擅長的。
畢竟皮膚有問題，有其內在的原因。
異位性皮膚炎需要認真看待，當患者長時間睡不好，會容易情緒低落、焦慮易怒，皮膚狀況不穩定也可能導致社交困難，甚至霸凌或自我封閉，這些骨牌效應影響深遠，不可不慎。
"Prevalence and Comorbidity of Atopic Dermatitis in Children: A Large-Scale Population Study Based on Real-World Data"，期刊摘要如下：
This study aimed at exploring atopic dermatitis（AD）prevalence in children and exhaustively analyzing their comorbidity. We conducted a descriptive analysis of their socio-demographic and comorbidity characteristics in the EpiChron Cohort（Aragón, Spain）. Adjusted odds ratios（OR）were calculated for each comorbidity using logistic regression models.
In total, 33,591 children had a diagnosis of AD, resulting in an overall prevalence of 15.5%. AD prevalence was higher in girls compared to boys, in 3–9-year-olds compared to children of other ages, and in Spanish children compared to those of other nationalities.
Multimorbidity was present in 43% of children, with the most frequent chronic comorbidities being asthma（13.1%）, psychosocial disorders（7.9%）, and visual impairment（7.8%）.
Many diseases were, regardless of their prevalence, statistically associated with AD. The strongest associations（odds ratio（OR）（95% confidence interval（CI）））were found in asthma（2.10（2.02–2.17））, allergic rhinitis（2.00 （1.91–2.10））, and irritable bowel syndrome（1.90（1.56–2.31））.
A better understanding of the array of comorbidities associated with AD in children might help improve their clinical management. Future longitudinal studies are encouraged to shed light on the potential underlying pathophysiological mechanisms involved in the identified associations.
